
This song was written and performed with his wife, Claudia Mori an actress turned record producer. Adriano suggests that the song is about "incommunicability" and to drive this point home they crafted lyrics that sound like English, but rarely make any sense beyond a couple linked words. Check out the video below that attempts to transcribe the lyrics:
The song is clearly bizarre, but the relentless beat, boomeranging horn stabs and growling guitars make it a freaky dancefloor classic. On top of that, the TV production looks like it was Fellini's attempt to choreograph and direct a classic 50s Elvis movie dance number. There might only be like 12 dancers, but thanks to the well positioned mirrors, it might as well be a google plus 1. The original version is from an Italian TV show. The actual song starts 1:15 in to the clip. If you want to watch it without the subtitles, here ya go:
Being an Italian pop star, naturally Adriano had to do a house remix.

Here's the original 45 version. The flip is called "Disc Jockey" and is basically the same song, utilizing that same fantastic crunching beat set against horn stabs and snarling guitars.
Adriano Celentano - Prisencolinensinainciusol (GW Ruff Edit)
And this is a great extended, re-edited and re-imagined version by legendary UK DJ Greg Wilson.